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JUN PROTEIN



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Jun protein

Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3' (PubMed, PubMed). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity). rows · JUN (Jun Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUN include Sarcoma and Primary Cutaneous T-Cell Lymphoma. Among its related pathways are NF-kappaB Pathway and Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2. JUN IS A KEY TRANSCRIPTIONAL REGULATOR OF THE UNFOLDED PROTEIN RESPONSE IN ACUTE MYELOID LEUKEMIA Abstract. The transcription factor JUN is frequently overexpressed in multiple genetic sub-types of acute myeloid INTRODUCTION. Although numerous genetic mutations and chromosomal aberrations that.

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Download scientific diagram | An AP-1 complex of a Fos and a Jun protein showing the molecular structure of the leucine zipper binding the two proteins. The Phospho-c-Jun (Ser63) kit enables the cell-based quantitative detection of cJun protein phosphorylated at Ser See more. Ease-of-use; High sensitivity. The Ishihara laboratory works in the field of protein engineering, with research foci in cancer immunotherapy, autoimmunity, and regenerative medicine.

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Activator protein 1 (AP1) is a heterodimeric transcription factor composed of members of the Jun and Fos family of basic leucine zipper proteins (Karin et al. Recombinant c-Jun is suitable for DNA and protein-protein interaction assays. The C-JUN protein, otherwise known as the Jun-Proto-Oncogene, is encoded in humans by the JUN gene and forms the AP-1 early response transcription factor in.

"Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP" Bohmann D., Bos T.J., Admon A. Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response. Full gene name according to HGNC. Jun proto-oncogene, AP-1 transcription factor subunit. Gene name i. Official gene symbol, which is typically a.

This gene is the putative transforming gene of avian sarcoma virus It encodes a protein which is highly similar to t he viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1pp31, a chromosomal region involved in both translocations and deletions in human www.akonchalovsky.rund: p Apr 30,  · The mammalian Jun proteins: redundancy and specificity Abstract. The AP-1 transcription factor is composed of a mixture of homo- and hetero-dimers formed between Jun and Fos Introduction. The AP-1 transcription factor participates in the control of cellular responses to stimuli that regulate. Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3' (PubMed, PubMed). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity).

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JUN IS A KEY TRANSCRIPTIONAL REGULATOR OF THE UNFOLDED PROTEIN RESPONSE IN ACUTE MYELOID LEUKEMIA Abstract. The transcription factor JUN is frequently overexpressed in multiple genetic sub-types of acute myeloid INTRODUCTION. Although numerous genetic mutations and chromosomal aberrations that. Recombinant Human c-Jun protein is a Baculovirus Full length protein, > 90% purity and validated in SDS-PAGE. Protein 1 Transcription Factor c-Jun. 1. Lluıs Riera-Sans2 and Axel Behrens3 c-Jun is a member of the AP-1 family of transcription factors, the activity of. Jun dimerization protein 2 (JDP2) regulates the APmediated activation of transcription. It can either form homodimers or form heterodimers with other. Jun dimerization protein 2. Synonyms. Jundm2, TIF. Feature Type. protein coding gene. IDs. MGI NCBI Gene: Alliance.
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